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Year : 2018  |  Volume : 6  |  Issue : 3  |  Page : 39-43

Posterior reversible encephalopathy syndrome

1 Associate professor, Dept of Medicine, MRMC., Kalaburagi, India
2 Associate Professor, Dept of Medicine, MRMC., Kalaburagi, India

Correspondence Address:
Sangram Biradar
Associate professor, Dept of genral medicine, M R M C, Kalburgi
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Source of Support: None, Conflict of Interest: None

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PRES is a reversible syndrome characterized by headache, seizure, altered consciousness and loss of vision PRES can be associated with a number of conditions, all of which result incerebralvasogenic oedema and white matter changes on imaging predominantly in the posterior cerebral hemispheres. The global incidence of PRES is unknown. It has been reported in patients ranging from 4 to 90 years of age, with most cases occurring in young-aged to middle-aged adults. A marked female preponderance is observed which may reflect some of the underlying causes. PRES occurs in association with a number of causes, most commonly hypertension, pre-eclampsia/eclampsia and immunosuppressive agents. This study reports a 31-year-old primigravida who presented with altered consciousness and focal seizure. The MRI of her brain showed E/O discrete area of T2,FLAIRhyperintensity in bilateral parito-occipital cortex and sub-cortical white matter. She was treated successfully with pregnancy termination, anti-hypertensives, anticonvulsants low molecular weight heparin, and supportive care. It is concluded that early diagnosis is important to prevent permanent neurologic damage and mortality.

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